What Is Codeine Phosphate?

Codeine Phosphate is a prescription opioid medication primarily used to relieve mild to moderate pain and to reduce cough. It belongs to the opioid (narcotic) class of drugs and works by changing how the brain and nervous system respond to pain. It’s often combined with other medications like paracetamol (acetaminophen) or ibuprofen to enhance its pain-relieving effects.

Medical Uses of Codeine Phosphate

1. Pain Relief:

   • Commonly prescribed for headaches, dental pain, menstrual cramps, and post-surgery pain.

2. Cough Suppression:

   • Used in certain prescription cough syrups to calm persistent coughs by acting on the brain’s cough center.

3. Diarrhea Control (less common):

   • In some formulations, it’s used to slow down bowel movement.

Codeine Phosphate is converted in the body to morphine through the liver enzyme CYP2D6. Morphine then binds to opioid receptors in the brain, blocking pain signals and producing a sense of relaxation or mild euphoria.

Common Side Effects

• Drowsiness or dizziness

• Constipation

• Nausea or vomiting

• Dry mouth

• Light-headedness

Dosage and Administration

• Typically prescribed in 15 mg to 60 mg doses every 4–6 hours as needed for pain, but dosage varies by individual.

• Should be taken exactly as prescribed.

• Avoid alcohol or other central nervous system depressants while using codeine.

Codeine Phosphate is an effective pain reliever and cough suppressant when used responsibly under medical supervision. However, due to its opioid nature, it carries significant risks if misused or taken without a prescription. Always follow your doctor’s guidance and never share your medication with others.